Wednesday, October 19, 2016

Multiple Endocrine Neoplasia (MEN)

The MENs are autosomal dominant endocrinal tumours syndrome.

There are three types: 1, 2A, 2B.

And to remember, this is how it goes: from 3Ps, to 2Ps, to 1P only. 

MEN 1
Pituitary Adenoma
Pancreatic Tumour*
Parathyroid Hyperplasia

MEN 2A
Parathyroid Hyperplasia
Phaeochromocytoma 
Medullary thyroid carcinoma

MEN 2B
Phaeochromocytoma
Medullary thyroid carcinoma 
Marfanoid body habitus 
Mucosal neuroma 

As you will have probably realised, from MEN 1 to MEN 2B, it goes from most Ps to only 1 P. hehe


**
MEN-1 gene is a tumour supressor gene

*comprises: gastrinoma, insulinoma, somatostatinoma, VIPoma, glucagonoma (GISVG)

No comments:

Post a Comment